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Diagnostic imaging can rule out coronary artery disease in patients with atypical chest pain

New York: Non-invasive diagnostic imaging can rule out coronary artery disease (CAD) in about 50% of women with atypical chest pain who are at relatively low risk for CAD, while exposing them to only a modest dose of radiation.

Friso van der Zant
Friso van der Zant

Coronary Computed Tomography Angiography (CCTA) combined with calcium scoring is a good first-line diagnostic tool for women, in whom CAD often presents as atypical chest pain and reduced radiation exposure to breast tissue is emphasized, according to a study published in Journal of Women’s Health.

In the article, Friso van der Zant and co-authors from Medical Centre Alkmaar, The Netherlands, evaluated the results of CCTA, a well-established, sensitive method of visualizing non-obstructive coronary artery disease, and calcium scoring to determine the presence of non-calcified plaques in the coronary arteries, among women over an 18-month period. The authors concluded that the ability to exclude a diagnosis of CAD in about half of patients can have a substantial impact on patient management.

“This study suggests that CCTA combined with calcium scoring is a useful diagnostic tool for excluding coronary artery disease in women with atypical chest pain, with minimal concerns about radiation exposure,” says Susan G Kornstein, editor-in-chief of Journal of Women’s Health, executive director of the Virginia Commonwealth University Institute for Women’s Health, Richmond, VA, and president of the Academy of Women’s Health.

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